lumea inca nu realizeaza pericolul! copiii nu par sa fie afectati, insa pot purta/raspandi covid. ce ne facem daca incep si copiii sa fie afectati, eventual printr-o mutatie, mai tarziu?
si cine crede ca chinezii nu fac acum propaganda ca sa fuga de raspundere, este cel putin naiv. trebuiau inchise toate pietele de animale vii in toata ASIA. de anul trecut de cand chinezii AU ASCUNS ce pateau.
ma parca vorbesc cu peretii, ma nu ati vazut seria cernobil, ma, nu poti ascunde, nu-ti merge cu natura!
cat priveste fituica "stiintifica" de la chinezi, va pun text sa cititi singuri. ar trebui sa va bateti cu ceva peste maini, sa aduceti speculatii goale drept dovezi intr-un sens sau altul.
asa spalat pe creier, cel putin al meu mai da semne de viata, din cand in cand.
The Huanan Seafood Wholesale Market boosted human-to-human transmission
at an early stage
Phylogenetic networks showed that bat-RaTG13-CoV was nested with Group B in Clade I, and
Clade II tends to be derived from Clade I, i.e., H1 and its descendant haplotypes were new
mutants from an ancestral haplotype in Clade I. The rooted network suggested two potential
evolutionary paths of available haplotypes that can be from H13 through H3 to H1 and H38, or
from H38 through H3 to H1 and H13 (Figure 3C). Both scenarios suggested that H3 might be the
ancestral haplotype of H1, as well as H13 or H38. H13 was only recovered from five Shenzhen
(Guangdong Province) samples, including patient 2 of the familial cluster (Chan et al., 2020). Two
derived haplotypes were also only found in Shenzhen of Guangdong Province (H14 from the
grandson of patient 2), and the other three haplotypes were found in three samples from Japan and
one sample from Arizona in the United States (Figure 3). According to an epidemiological study,
the Shenzhen family should have been infected during their visit in Wuhan (Chan et al., 2020).
This suggests that H13 originated from Wuhan. Genetically, haplotypes of Group A have links to
only Wuhan haplotype H3 (only EPI_ISL_406801, with no link to the Huanan Market). It is
possible that H13 was newly derived from H3 (Figure 3C) and did not spread in Wuhan, or that
three repatriated Japanese were infected by H13 in Wuhan (The Asahi Shimbun, 2020), or that no
samples have been sequenced yet. H38 has three genomes from the same patient (Table S1), who
was the first identified infected patient in the United States (Holshue et al., 2020). He should have
been infected while visiting his family in Wuhan, China. The original source of H38 can be
explained as that of H13, which is also derived from H3 (Figure 3C), and the derived H45 was
from a Chongqing patient who was working in Wuhan.
The H3 haplotype has only one sample from Wuhan, which was not linked to the Huanan Market
(Lu et al., 2020b), and the other samples in this group were from outside of Wuhan (Figure 3A).
Noteworthily, all the samples from the Market belonged to H1 or its derived haplotypes (H2,
H8-H12, see Figure 2 and Table S1), indicating that there were circulated infections within the
market in the short term. Other researchers have argued that the source of the coronavirus in the
Market should be imported from elsewhere, or at least it should be not the single source of
SARS-CoV-2 (Cohen, 2020). In this study, evolutionary relationships indicated that H1 and its
descendant haplotypes from the Market should be derived from H3 (Figures 3 and 4). H3 mutated
to the H1 by two substitutions, and none of the Market samples encoded H3 in the currently
available samples, suggesting that H3 might have originated and spread outside of the Market
before an early stage of population expansion. The non-synonymous mutation from H3 to H1
might have enhanced the infectiousness of SARS-CoV-2, and a functional characterization should
be performed to confirm this speculation. It is possible that SARS-CoV-2 in the Market had been
transmitted from other places (Figure 3D), or at least, that the Market did not host the original
source of SARS-CoV-2 (Cohen, 2020). As the first identified infected patients had no link to the
Market (Huang et al., 2020), it is possible that infected humans transmitted the H1 haplotype of
SARS-CoV-2 to workers or sellers in the market, after which it rapidly circulated there due to its
special surroundings. The crowded market boosted SARS-CoV-2 transmissions to buyers and
spread it to the whole city in early December 2019, corresponding to the estimated population
expansion time. Due to insufficient samplings from Wuhan in the currently available samples, it is
not clear whether H3 never appeared in the Market, or H1 was quickly derived from H3 to adapt
in the Market. The early stage environmental samples from the Market (Xinhua, 2020) might
provide additional evidence for this speculation
tldr: hocus pocus we don't know, but it wasn't us.
Tu bati campii pentru ca nici n-ai deschis linkul cu studiul.
Si nu doar ca cifrele alea sunt verificate pentru ca sunt disponibile oricui, dar pe alea s-a bazat toata comunitatea stiintifica la momentul respectiv si tot alea stau la baza studiilor ulterioare (plus datele care se adauga in permanenta).
Si tot pe alea se bazeaza si alt studiu facut in vest, care impinge originea contaminarii din China pana spre sfarsitul lui octombrie/inceputul lui noiembrie. La primii 5 cei mai vechi subiecti contaminati nu s-a gasit legatura comuna cu piata de animale din Wuhan, ca despre asta e vorba.
baaaaa
nu exista cifre! arata-mi DATA. SCIENTIFIC DATA. PEER REVIEW!
si daca tot ma jignesti pe gratis, te invit sa argumentezi pana nu te fac eu cu ou si otet..poate. daca ma cobor la nivelul tau.
Topic: Virusi, gripe, info & stuff (Read 167527 times)
